4,668 research outputs found

    Some Comments on: Existence of Solutions of Abstract Nonlinear Second-Order Neutral Functional Integrodifferential Equations

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    We establish the existence of mild solutions for a class of abstract second-order partial neutral functional integro-differential equations with infinite delay in a Banach space using the theory of cosine families of bounded linear operators and Schaefer\u27s fixed-point theorem

    Refining bushing power factor and capacitance analysis through statistics

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    Use of statistics opens the door for enhancing bushing power factor / capacitance analysis. The tool, in¬formed by a database with more than 6 million tests, tailors the diagnostic limits by determining what is sta¬tistically normal for a specific type, manufacturer, and voltage rating of a bushing. More precisely, it com¬putes deviations of power factor and capacitance from a benchmark. It then determines the probability dis¬tribution that best fits the resulting dataset. Once the data is mathemat¬ically characterized, the mean and standard deviations are computed. In the end, the bushing in question is assessed based on how it statistical¬ly compares to the rest

    Refining bushing power factor and capacitance analysis through statistics

    Get PDF
    Use of statistics opens the door for enhancing bushing power factor / capacitance analysis. The tool, in¬formed by a database with more than 6 million tests, tailors the diagnostic limits by determining what is sta¬tistically normal for a specific type, manufacturer, and voltage rating of a bushing. More precisely, it com¬putes deviations of power factor and capacitance from a benchmark. It then determines the probability dis¬tribution that best fits the resulting dataset. Once the data is mathemat¬ically characterized, the mean and standard deviations are computed. In the end, the bushing in question is assessed based on how it statistical¬ly compares to the rest

    Mutations to the caveolin scaffolding domain reduces Caveolin-1 targeting of glycolytic enzymes to lymphocyte membranes [abstract]

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    Abstract only availablePreviously, we found caveolin (CAV-1) expressed by transfection in cultured lymphocytes induced caveolae formation and targeted the glycolytic enzyme phosphofructokinase (PFK) to the membrane. We also found CAV-1 targets other glycolytic enzymes such as aldolase (ALD)and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to the plasma membrane in the CAV-1 transfected lymphocytes. Here we hypothesized that if a mutant CAV-1 (which has essential aromatic residues in the caveolin scaffolding domain (CSD) mutated) is expressed in the lymphocyte then colocalization of the glycolytic enzyme PFK with CAV-1 will be reduced. We tested this hypothesis by comparing the colocalization of CAV-1 with the glycolytic enzymes PFK, ALD and GAPDH in lymphocytes which expressed either a wild type CAV-1 (WT) or a mutant CAV-1 which had either one mutation (SM) or two mutations (DM) in the CSD. Colocalization analysis by confocal microscopy of cells immunoassayed for CAV-1 and ALD was 76.59% in lymphocytes transfected with CAV-1 WT, 23.96% in lymphocytes transfected with CAV-1 SM, and 58.74% in the lymphocytes transfected with CAV-1 DM. Analysis of colocalization of the enzymes PFK, GAPDH, and ALD with CAV-1 averaged 65.17% for the CAV-1 WT cells, 49.29% for the CAV-1 SM cells and 50.81% for the CAV-1 DM cells. The shift in distribution of glycolytic enzymes and CAV-1 in the CAV-1 WT, the CAV-1 SM or DM CAV-1 types indicates that a single mutation to the CSD reduces membrane targeting of glycolytic enzymes, and two mutations in the CSD produces retention of CAV-1 in the cytosol. These results suggest that an intact CSD domain is essential to the CAV-1 targeting of glycolytic enzymes to the membrane

    A method to monitor poverty dynamics among microfinance clients: An example using survey data from Bangladesh

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    This article presents a practical methodology to monitor poverty changes among microfinance clients using available household panel data. As an example, it presents an estimation of the net number of people that rose above the 1/daypovertylinewhilemembersofGrameenBankandBRACduring1990to2006.Theproposedmethodcontributestoongoingeffortsfrommicrofinancepractitionerstoverifywhethertheirclientsaremovingoutofpovertyandvalidatemanagementstrategiesaimingtotargetnewpoorclients,andincreasetheirshareofpoorclientsovertime.Estimatesshowthatabout6.6millionpeopleroseabovethe1/day poverty line while members of Grameen Bank and BRAC during 1990 to 2006. The proposed method contributes to on-going efforts from microfinance practitioners to verify whether their clients are moving out of poverty and validate management strategies aiming to target new poor clients, and increase their share of poor clients over time. Estimates show that about 6.6 million people rose above the 1/day poverty line in 1990-2006 while members of Grameen or BRAC. This represents about 40 percent of the total number of poor people that crossed this poverty line during the same time period at the national level, which validates targeting strategies to reach the poor
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